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AstraZeneca
Rueil-Malmaison
maintenant
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AstraZeneca R&D
- Head of Computational and Support Chemistry Group
2011 - maintenant
Management of the Computational Medicinal Chemistry, NMR and Support Chemistry groups at Reims. Drug Designer supporting Oncology projects. Involved in global AZ initiatives and collaborations. Acting as Associate Director in the management of the Reims research unit.
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AstraZeneca
- Team Leader Computational and Analytical Chemistry
Rueil-Malmaison
2007 - 2010
Management of the computational chemistry, physico-chemical and NMR units. Responsible for the molecular modelling studies and data mining to support oncology projects in the Reims Research Centre. Strongly involved in drug design at lead optimisation stage.
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AstraZeneca R&D
- Team Leader Computational Chemistry - Library Design
2001 - 2004
Responsable for the local implementation of a design and make process of targeted chemical libraries aimed at finding new mode of action in the kinase field (prevention of activation, allosteric inhibition) ).Management of 2 post-doctoral students. Active role in a global AZ group investigating new approaches to Kinases inhibition.
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AstraZeneca
- Team Leader Computational Chemistry
Rueil-Malmaison
1986 - 2006
Support of many lead identication and optimisation projects in inflamation, infection and oncology, through computational and medicinal chemistry expertise. Dealing with a high variety of target families.Impact on succesful transition to development phase of many different projects
